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Genetic link between schizophrenia and bipolar disorder?

Some interesting news from the geeks in white coats suggests there may be a common genetic basis for schizophrenia and bipolar disorder.

Three different international studies investigated the genetic basis of schizophrenia by pooling their analysis of about 15,000 patients and nearly 50,000 healthy subjects to find that thousands of tiny genetic mutations – [...]

The Science and Science of Psychiatry?

NeuroAnalyis – An interview with Avi Peled, M.D.

Back in July 2008 Mr Ian was on a rant. A rant about professional exclusivity in the realm of understanding and curing mental disorders – how one profession purports to beholden the knowledge and the cure for “les maladies de la tête“.

It was a passing storm long forgotten – until I recently came across a psychiatrist in Israel who has been raising awareness of his theories on a potential cure for mental disorder.

NeuroAnalysis is the brainchild of Avi Peled, M.D. and is the title of his 2008 book explaining all about understanding mental disorder as requiring a multi-speciality approach to science-based diagnostics and treatment.

Avi has a webpage: http://neuroanalysis.googlepages.com/home

On there he describes his theory on how mental disorder diagnostics can become scientifically based by producing profiles of brain function which more or less identify which neurons or networks are misbehaving by comparison to other optimally functioning networks. Such science would obviously render the subjective and often contentious DSM/ICD as a redundant artefact, consigned to the history museums of Bedlam.

Clinical Brain Profiling (CBP)

Psychiatric mental disorders can be formulated in terms of disturbances to optimal neural network dynamics in the brain. CBP reformulates psychiatric mental disorders as disorders of the optimal neural network organization of the brain. It is based on excellent scientific work by many neuroscientists and psychiatrists, never-the-less it still needs to stand the proof (or refute) of scrutinizing empirical appreciation.

I asked Avi if he’d be willing enough to give a brief explanation of his cause to us here at Mental Nurse and he was only too willing to oblige in the form of answering several questions over a course of emails.


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